Loretta J Nastoupil Selected Research

cell-associated neurotoxicity

12/2021	Management of Immune-Related Adverse Events in Patients Treated With Chimeric Antigen Receptor T-Cell Therapy: ASCO Guideline.
12/2020	Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas.
1/2020	Clinical and radiologic correlates of neurotoxicity after axicabtagene ciloleucel in large B-cell lymphoma.

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Loretta J Nastoupil Research Topics

Disease

25	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 04/2022 - 12/2012
18	B-Cell Lymphoma (Lymphoma, B Cell) 10/2022 - 01/2016
15	Neoplasms (Cancer) 10/2022 - 09/2012
14	Lymphoma (Lymphomas) 10/2022 - 05/2015
12	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2022 - 09/2012
6	Non-Hodgkin Lymphoma (Lymphosarcoma) 02/2019 - 09/2013
5	Hodgkin Disease (Hodgkin's Disease) 07/2020 - 01/2017
3	Cytokine Release Syndrome 10/2022 - 12/2021
3	cell-associated neurotoxicity 12/2021 - 01/2020
2	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 09/2022 - 01/2016
2	Diarrhea 01/2022 - 01/2021
2	Exanthema (Rash) 01/2022 - 11/2015
2	Cardiotoxicity 12/2021 - 10/2018
2	T-Cell Lymphoma (Lymphoma, T Cell) 01/2020 - 01/2016
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2019 - 09/2013
2	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 02/2015 - 10/2013
1	Hematologic Neoplasms (Hematological Malignancy) 10/2022
1	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 09/2022
1	Aseptic Meningitis 01/2022
1	Nausea 01/2022
1	Pancreatitis 01/2022
1	Cytopenia 10/2021
1	Long Term Adverse Effects 10/2021
1	Opportunistic Infections (Opportunistic Infection) 10/2021
1	Hyperglycemia 01/2021
1	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 01/2021
1	Colitis 01/2021
1	Hypertension (High Blood Pressure) 01/2021
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020
1	COVID-19 01/2020
1	Disease Progression 02/2019
1	Leukemia 10/2018
1	Pneumonia (Pneumonitis) 10/2018
1	Fever (Fevers) 10/2018
1	Febrile Neutropenia 10/2018
1	Thrombocytopenia (Thrombopenia) 01/2018
1	Neutropenia 01/2018

Drug/Important Bio-Agent (IBA)

23	Rituximab (Mabthera)FDA Link 01/2022 - 10/2012
14	Chimeric Antigen ReceptorsIBA 10/2022 - 01/2020
9	axicabtagene ciloleucelIBA 10/2022 - 01/2020
6	Lenalidomide (CC 5013)FDA Link 01/2022 - 05/2015
5	Prednisone (Sone)FDA LinkGeneric 10/2018 - 07/2013
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 11/2015 - 07/2013
4	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2015 - 07/2013
4	Vincristine (Oncovin)FDA LinkGeneric 11/2015 - 07/2013
3	tocilizumab (atlizumab)FDA Link 01/2022 - 01/2020
2	Alkylating AgentsIBA 04/2022 - 09/2013
2	EnzymesIBA 01/2022 - 01/2021
2	pembrolizumabIBA 01/2022 - 01/2017
2	Monoclonal AntibodiesIBA 01/2022 - 09/2013
2	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2021 - 10/2021
2	carboxyl radical (COO-)IBA 01/2021 - 01/2021
2	ibrutinibIBA 12/2020 - 02/2019
2	purineIBA 10/2018 - 09/2013
2	AntibodiesIBA 01/2017 - 07/2015
2	fludarabineIBA 01/2017 - 05/2015
2	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2017 - 11/2016
2	Biological ProductsIBA 01/2016 - 09/2015
1	Pharmaceutical PreparationsIBA 10/2022
1	tisagenlecleucelIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	omega-Chloroacetophenone (Mace)IBA 01/2022
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022
1	UbiquitinIBA 01/2022
1	Cell-Free Nucleic AcidsIBA 01/2022
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2022
1	PlatinumIBA 01/2022
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 12/2021
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2021
1	copanlisibIBA 01/2021
1	TOR Serine-Threonine KinasesIBA 01/2021
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2021
1	Bleomycin (Blenoxane)FDA LinkGeneric 07/2020
1	Immunomodulating AgentsIBA 01/2020
1	MLN 8237IBA 01/2020
1	romidepsin (FK228)FDA Link 01/2020
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2020
1	ublituximabIBA 02/2019
1	umbralisibIBA 02/2019
1	NucleosidesIBA 10/2018
1	Antiviral Agents (Antivirals)IBA 10/2018
1	Acyclovir (Aciclovir)FDA LinkGeneric 10/2018
1	FluoroquinolonesIBA 10/2018
1	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 10/2018
1	Amoxicillin (Wymox)FDA LinkGeneric 10/2018
1	Clindamycin (Cleocin)FDA LinkGeneric 10/2018
1	Penicillins (Penicillin)FDA Link 10/2018
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2018
1	Carboplatin (JM8)FDA LinkGeneric 01/2018
1	Ifosfamide FDA LinkGeneric 01/2018

Therapy/Procedure

40	Therapeutics 10/2022 - 12/2012
15	Drug Therapy (Chemotherapy) 10/2022 - 09/2012
10	Radiotherapy 10/2021 - 07/2013
3	Combined Modality Therapy 01/2021 - 10/2019
3	Immunotherapy 11/2018 - 07/2015
2	Breast Implants (Breast Implant) 09/2022 - 01/2016
2	Radioimmunotherapy 03/2015 - 12/2012
1	Autologous Transplantation 01/2021
1	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2020
1	Hematopoietic Stem Cell Transplantation 10/2018